Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity linked to bortezomib, a proteasome inhibitor used in the therapy of a number of myeloma. Its synthesis or review is important for guaranteeing the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets unique sorts of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the manufacturing course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to take care of breast most cancers, and these intermediates are involved in its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the therapy of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in managing cancers 5 including ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the treatment method of colorectal most cancers and modest mobile lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, which have several purposes, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which are Utilized in foods, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication CAS NO. 875573-63-0 applied to control form two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).